Limidax XR
Stinging Nettle

Found in Limidax as: Nettle Leaf Extract.

The Research and Science Behind Nettle Leaf Extract

Updated on March 23, 2015

Nettle Leaf Extract is derived from the Stinging Nettle plant, also known as Uritica dioica. The ingredient has a track record of usage. Although initially indigenous to Africa and parts of Asia, the herb can now be located in all temperate zones across continents. Studies across universities and clinical studies have shown that Nettle can be a relaxing and nourishing herb. The nutrients in the nettle plan are highly bio-active and may help support the nourishment of blood, lymph, hormones, and neurotransmitters



  1. Please read the research for yourself: The beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat. Authors: Toldy A, Atalay M, Stadler K, Sasvári M, Jakus J, Jung KJ, Chung HY, Nyakas C, Radák Z. The Direct Link to the Study is: http://www.ncbi.nlm.nih.gov/pubmed/19071007
    Any questions? Our neuroscientists are ready to answer your questions. Reach out to us: support@limidax.com

  2. Please read the research for yourself: The effect of exercise and nettle supplementation on oxidative stress markers in the rat brain. Authors: Toldy A, Stadler K, Sasvári M, Jakus J, Jung KJ, Chung HY, Berkes I, Nyakas C, Radák Z. The Direct Link to the Study is: http://www.ncbi.nlm.nih.gov/pubmed/15862920
    Any questions? Our neuroscientists are ready to answer your questions. Reach out to us: support@limidax.com


The Beneficial Effects of Nettle Supplementation on Memory

Nettle supplementation decreased the level of reactive oxygen species, measured by electron paramagnetic resonance, and the DNA binding activity of NF -kappaB. Researchers concluded from the study: "The data reveal[s] that nettle supplementation has an effective antioxidant role, down-regulates the inflammatory transcription factors, and could also promote learning performance in the brain. You can read the full study yourself through The U.S. National Library of Medicine

Nettle Supplementation on Oxidative Stress Markers

Within the study, rats were divided into groups subjected to swimming training (6 weeks) or to nettle supplementation (8 weeks) or to a combination of these two treatments. Nettle supplementation resulted in a decreased concentration of free radicals in both cerebellum and frontal lobe. The protein content of nerve growth factor (NGF), and brain-derived neurotrophic factors (BDNF) was evaluated by E-Max ImmunoAssay in the cerebellum. The researchers concluded: "Nettle supplementation reduces the free radical concentration and increases the DNA binding of AP-1 in the brain. Nettle was found to be an effective antioxidant and possible antiapoptotic supplement promoting cell survival in the brain." You can read the full study yourself through The U.S. National Library of Medicine